Extracorporeal Selective Chloride Removal By Electrodialysis: An Innovative Treatment For Respiratory and Metabolic Acidosis
نویسندگان
چکیده
Introduction Acidosis is a frequent disorder among critically ill patients. When patient compensatory responses fail to restore a normal pH, administration of sodium bicarbonate (NaHCO3) or renal replacement therapy may be required. Intravenous NaHCO3 increases plasma Strong Ion Difference ([SID] = [Na] + [K] [Cl]) and HCO3 concentration by raising Na concentration. Although effective, this treatment is not devoid of complications, such as hypernatremia, hyperosmolarity and fluid overloading[1]. Selective chloride (Cl) removal, by increasing SID in an alternative way, may allow a rapid correction of acidosis without altering plasma osmolality and Na concentration.
منابع مشابه
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